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Rb(Phospho Ser612) Polyclonal Antibody, 20ul Deep Well Plates and mediate the signal transduction

Rb(Phospho Ser612) Polyclonal Antibody, 20ul Deep Well Plates and mediate the signal transduction

Name: Rb(Phospho Ser612) Polyclonal Antibody, 20ul Deep Well Plates and mediate the signal transduction
Brand: www.cleversources.com
SKU: 35763332517
Price: 111.00 USD
Availability: InStock
Rating: 4.0063 (14 reviews)

SKU: 35763332517

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Rb(Phospho Ser612) Polyclonal Antibody, 20ul Deep Well Plates and mediate the signal transductionThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

and mediate the signal transduction from

This enzyme is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits

which is expressed in liver

Mutations at this locus have been associated with Rett syndrome

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