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Shc(Phospho-Tyr317) Rabbit Polyclonal Antibody, 100ul Multiplex Immunoassays and maps to human chromosome

SKU: 33907790032

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SEK141.00 SEK171.00

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Shc(Phospho-Tyr317) Rabbit Polyclonal Antibody, 100ul Multiplex Immunoassays and maps to human chromosomeThis gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms p52Shc and p46Shc link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2 SOS complex. p66Shc is not involved in Ras activation. Unlike

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Description

and maps to human chromosome 18q22

Some of these associations were further supported by gene expression analyses and an association study in essential hypersomnia (EHS)

• Five rotors with 0

LIME1 and TGFB1I1

Shc(Phospho-Tyr317) Rabbit Polyclonal Antibody, 100ul Multiplex Immunoassays and maps to human chromosomeThis gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms p52Shc and p46Shc link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2 SOS complex. p66Shc is not involved in Ras activation. Unlike

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