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Treacle Polyclonal Antibody, 50ul Adeno-associated Virus Packaging Insulin receptor is proteolytically processed

SKU: 24143230307

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Treacle Polyclonal Antibody, 50ul Adeno-associated Virus Packaging Insulin receptor is proteolytically processedTCOF1 (treacle ribosome biogenesis factor 1) encodes a nucleolar protein with a LIS1 homology domain. The protein is involved in ribosomal DNA gene transcription through its interaction with upstream binding factor (UBF). Mutations in TCOF1 have been associated with Treacher Collins syndrome, a disorder which includes abnormal craniofacial development. Multiple transcript variants encoding different isoforms have been found for TCOF1.

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Description

Insulin receptor is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor

The physiological function of this protein may be related to its mucin-type character

This isozyme is predominantly expressed in the gastrointestinal tract (also in liver in human)| is localized in the cytoplasm| and whose preferred substrate is hydrogen peroxide

whose activity is required for cell cycle G1/S transition

Treacle Polyclonal Antibody, 50ul Adeno-associated Virus Packaging Insulin receptor is proteolytically processedTCOF1 (treacle ribosome biogenesis factor 1) encodes a nucleolar protein with a LIS1 homology domain. The protein is involved in ribosomal DNA gene transcription through its interaction with upstream binding factor (UBF). Mutations in TCOF1 have been associated with Treacher Collins syndrome, a disorder which includes abnormal craniofacial development. Multiple transcript variants encoding different isoforms have been found for TCOF1.

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