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RARBeta Polyclonal Antibody, 50ul Miscellaneous This protein has been observed

SKU: 21832393677

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RARBeta Polyclonal Antibody, 50ul Miscellaneous This protein has been observedRARB encodes retinoic acid receptor beta, a member of the thyroid steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating

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Description

This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia

ring chromosome 20 epilepsy syndrome and Alagille syndrome

with this polypeptide being present in both muscle and non-muscle tissues

The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions

RARBeta Polyclonal Antibody, 50ul Miscellaneous This protein has been observedRARB encodes retinoic acid receptor beta, a member of the thyroid steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating

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