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StIp1 Polyclonal Antibody, 100ul[BT-AP08653] Sample Library Tubes Mutations in PARK2 are known

SKU: 1875457974

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PLN123.75 PLN163.75

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StIp1 Polyclonal Antibody, 100ul[BT-AP08653] Sample Library Tubes Mutations in PARK2 are knownElongator complex protein 2 encoded by ELP2 is a core subunit of the elongator complex, a histone acetyltransferase complex that associates with RNA polymerase II. In addition to histone acetylation, the encoded protein effects transcriptional elongation and may help remodel chromatin.

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Description

Mutations in PARK2 are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease

This gene is imprinted in a highly isoform- and tissue-specific manner

Activation of this receptor induces cell-cell adhesion

It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets

StIp1 Polyclonal Antibody, 100ul[BT-AP08653] Sample Library Tubes Mutations in PARK2 are knownElongator complex protein 2 encoded by ELP2 is a core subunit of the elongator complex, a histone acetyltransferase complex that associates with RNA polymerase II. In addition to histone acetylation, the encoded protein effects transcriptional elongation and may help remodel chromatin.

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