SHP-1(Phospho-Tyr564) Rabbit Polyclonal Antibody, 100ul Micro Centrifuge Tubes Aberrations in chromosome 1 are

Aberrations in chromosome 1 are found in a variety of cancers

a homotetrameric protein

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The encoded protein couples with the Gs alpha subunit and stimulates adenylate cyclase to activate the cyclic AMP-dependent signaling pathway

SHP-1(Phospho-Tyr564) Rabbit Polyclonal Antibody, 100ul Micro Centrifuge Tubes Aberrations in chromosome 1 areThe protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth differentiation mitotic cycle and oncogenic transformation. N terminal part of this PTP contains two tandem Src homolog (SH2) domains which act as protein phospho tyrosine binding domains and mediate the interaction of this PTP with its substrates.