RCC1 Polyclonal Antibody, 50ul Vortex Mixer Colocalizes with ITPR1

Colocalizes with ITPR1

In the autosomal dominant form

Mutations in this gene have been associated with Kenny-Caffey syndrome (KCS) type 2 and the more severe osteocraniostenosis (OCS| also known as Gracile Bone Dysplasia)| both characterized by short stature| hypoparathyroidism| bone development abnormalities| and hypocalcemia

and is regulated by the NURD nucleosome remodeling and histone deacetylase complex

RCC1 Polyclonal Antibody, 50ul Vortex Mixer Colocalizes with ITPR1The Ras family small GTPase Ran is involved in nuclear envelope formation, assembly of the mitotic spindle and nuclear transport. Like other small GTPases, Ran is active in its GTP bound form and inactive in its GDP bound form. Nuclear RanGTP concentration is maintained through nuclear localization of guanine nucleotide exchange factor (GEF) activity, which catalyzes the exchange of bound GDP for GTP. RCC1 (regulator of chromatin condensation 1) is