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CD232 Polyclonal Antibody, 50ul Polyclonal Antibody Preparation TSC1 (tuberous sclerosis 1) encodes

SKU: 16189286299

4.2
USD162.00 USD192.00

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CD232 Polyclonal Antibody, 50ul Polyclonal Antibody Preparation TSC1 (tuberous sclerosis 1) encodesPLXNC1 encodes a member of the plexin family. Plexins are transmembrane receptors for semaphorins, a large family of proteins that regulate axon guidance, cell motility and migration, and the immune response. The plexin C1 and its ligand regulate melanocyte adhesion, and viral semaphorins may modulate the immune response by binding to this receptor. The encoded protein may be a tumor suppressor protein for melanoma. Alternatively spliced transcript

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Description

TSC1 (tuberous sclerosis 1) encodes a growth inhibitory protein thought to play a role in the stabilization of tuberin

demonstrating glutathione S-transferase and peroxidase activities

|PTM:Phosphorylation at 'Ser-903' and 'Ser-907' primes p105 for proteolytic processing in response to TNF-alpha stimulation

The C-terminal half of the protein shares homology with trypsin-like peptidases and it contains a PCNA-interacting peptide (PIP) box| that is necessary for its co-localization with proliferating cell nuclear antigen (PCNA)

CD232 Polyclonal Antibody, 50ul Polyclonal Antibody Preparation TSC1 (tuberous sclerosis 1) encodesPLXNC1 encodes a member of the plexin family. Plexins are transmembrane receptors for semaphorins, a large family of proteins that regulate axon guidance, cell motility and migration, and the immune response. The plexin C1 and its ligand regulate melanocyte adhesion, and viral semaphorins may modulate the immune response by binding to this receptor. The encoded protein may be a tumor suppressor protein for melanoma. Alternatively spliced transcript

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