Rb(Phospho Ser608) Polyclonal Antibody, 20ul Liquid Storage Consumables In nonmuscle cells| the cytoskeletal

In nonmuscle cells| the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions| where it is involved in binding actin to the membrane

|cofactor:Binds 1 Fe(3+) ion per subunit

Some transcripts contain a differentially methylated region (DMR) at their 5' exons| and this DMR is commonly found in imprinted genes and correlates with transcript expression

The 5’ RACE technology amplifies complementarity-determining regions (CDRs) of B cell receptors (BCRs) or T cell receptors (TCRs)

Rb(Phospho Ser608) Polyclonal Antibody, 20ul Liquid Storage Consumables In nonmuscle cells| the cytoskeletalThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.