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Fifth Human Niagen Study That Demonstrates Effectiveness: A clinical trial published in Scientific Reports in 2019 concludes Niagen both safely and effectively increases NAD+ levels in a dose-dependent manner in healthy overweight adults. The study used an eight-week randomized, double-blind, placebo-controlled trial to conduct its evaluation

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Research using gene expression profiling has shown that IGF1 LR3 alters the expression of many genes involved in protein synthesis, cell proliferation, and body function within the first week of use