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Mitochondrial fission is controlled by dynamin-related protein 1 (Drp1) and mitochondrial fission protein 1 (FIS1)

To counter this limitation, a group of GLP-1 receptor agonists (GLP-1RAs), which are resistant to DPP4-mediated degradation [32], have been developed and shown to be effective in treating T2DM and obesity [33]