Rb Polyclonal Antibody, 100ul[BT-AP07691] sgRNA Oligos RGS14 encodes a member of

RGS14 encodes a member of the regulator of G-protein signaling family

This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level

NF-kappa-B p50 subunit interacts with NCOA3 coactivator| which may coactivate NF-kappa-B dependent expression via its histone acetyltransferase activity

While the interaction with CBL is apparently mediated via the hydrophobic region of this domain

Rb Polyclonal Antibody, 100ul[BT-AP07691] sgRNA Oligos RGS14 encodes a member ofThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.