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falciparum malaria, and partly because they developed drug-induced AHA on top of the anaemia (secondary to malaria and to other causes) that most of them already had before starting treatment

The SELECT trial, which studied semaglutide in cardiovascular outcomes across nearly 18,000 people with obesity and heart disease risk, similarly found no elevated musculoskeletal injury rates compared to control

Both lightly and darkly pigmented skin contain similar numbers of melanocytes, [12] with difference in skin color due to differences the packing of eumelanin into the melanosomes of keratinocytes: those in dark-toned skin are "packaged into peri-nuclear distributed, ellipsoid" melanosomes while those light-tone skin are "assembled into clustered small, circular melanosomes"

Second, the use of cis-acting variants as instrumental variables provided a clearer insight into the potential causal relationship between gene expression and disease risk