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A statistically significant increase in thyroid C-cell adenomas was observed in males and females at all dose levels, and a statistically significant increase in thyroid C-cell carcinomas was observed in males at greater than or equal to 0.01 mg/kg/day, at clinically relevant exposures

Indeed, age-related declines in skeletal muscle mass index (SMI) and function often occur in parallel with increases in total FM, while the clinical course of obesity is characterized by a range of risk factors for sarcopenia, including elevated oxidative stress, inflammation, and the burden of NCDs [15, 16]

This is a critical point to understand because acetaldehyde is significantly more toxic than alcohol itself