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Out of the three options, Thesis has an edge here because it uses some shorter lists of ingredients in doses that are sometimes lower than what human studies confirm to be effective

Copper toxicity is a theoretical concern given that GHK-Cu chelates copper ions

Compounded versions of semaglutide existed (and were heavily marketed through telehealth platforms), but the FDA is cracking down on compounders making GLP-1 products now that the drug shortage has ended