Mouse Chondroitin Sulfate Proteoglycan 4, CSPG4 ELISA Kit , 96T Peptide Synthesis Defects in this gene can

Defects in this gene can lead to the calcification of joints and arteries

for DM0424

Allelic variants of this gene are associated with autosomal dominant mental retardation-32

Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides (PubMed: 21078852)

Mouse Chondroitin Sulfate Proteoglycan 4, CSPG4 ELISA Kit , 96T Peptide Synthesis Defects in this gene canProteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. May also inhibit neurite outgrowth and growth cone collapse during axon regeneration. Cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate. Binds through its extracellular N terminus growth factors, extracellular matrix proteases modulating their activity.