IBP5 Polyclonal Antibody, 100ul Molecular Sciences Mutations in this gene and/or

Mutations in this gene and/or its regulatory regions cause severe obesity

TRAFs are composed of an N-terminal cysteine/histidine-rich region containing zinc RING and/or zinc finger motifs

A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin

Enhances the transcriptional repressor activity of NR1D1 through stabilization of NR1D1 protein levels by preventing its ubiquitination and subsequent degradation (PubMed: 18235501

IBP5 Polyclonal Antibody, 100ul Molecular Sciences Mutations in this gene and/orIGF binding proteins prolong the half life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.,Contains 1 IGFBP N terminal domain.,Contains 1 thyroglobulin type 1 domain.,tissue specificity: Osteosarcoma, and at lower levels in liver, kidney and brain.,