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MLL Monoclonal Antibody, 100ul Adeno-associated Virus Packaging Microtubule affinity regulating kinase 3

SKU: 84801719508

4.1
USD135.00 USD165.00

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MLL Monoclonal Antibody, 100ul Adeno-associated Virus Packaging Microtubule affinity regulating kinase 3This gene encodes a transcriptional coactivator that plays an essential role in regulating gene expression during early development and hematopoiesis. The encoded protein contains multiple conserved functional domains. One of these domains, the SET domain, is responsible for its histone H3 lysine 4 (H3K4) methyltransferase activity which mediates chromatin modifications associated with epigenetic transcriptional activation. This protein is processed

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Description

Microtubule affinity regulating kinase 3 encoded by MARK3 is activated by phosphorylation and in turn is involved in the phosphorylation of tau proteins MAP2 and MAP4

Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma

The protein encoded by this gene forms a multiprotein BBSome complex with seven other BBS proteins

FOXD4L5 and FOXD4L6) are encoded by a strongly repeated region of the 9q12 chromosome region

MLL Monoclonal Antibody, 100ul Adeno-associated Virus Packaging Microtubule affinity regulating kinase 3This gene encodes a transcriptional coactivator that plays an essential role in regulating gene expression during early development and hematopoiesis. The encoded protein contains multiple conserved functional domains. One of these domains, the SET domain, is responsible for its histone H3 lysine 4 (H3K4) methyltransferase activity which mediates chromatin modifications associated with epigenetic transcriptional activation. This protein is processed

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