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I tell my patients struggling with weight: its never too late to get your health back. Amanda Taylor, 31, Denver, Colorado Im nearly seventy and have battled obesity and type 2 diabetes for years

The SmPC recommends gradual dose titration to minimise gastrointestinal side effects: starting with 2.5 mg once weekly for 4 weeks, then increasing in 2.5 mg increments at minimum 4-week intervals to a maximum of 15 mg based on response and tolerability

ERR gamma functions prominently in heart tissue, where it supports the enormous energy demands of continuous cardiac contraction

The answer is generally yes, as long as you maintain approximately weekly spacing going forward