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Mnzel, T., Daiber, A., Ullrich, V

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According to a systematic review in the Journal of Psychiatric Research , as well as Cleveland Clinic, some of the most common triggers of manic episodes include: Medications, such as antidepressants Overstimulating environments (loud noise, bright lights, big crowds) Stress or great life changes (such as bereavement, childbirth, divorce, or being laid off) Problems sleeping or insufficient sleep Substance use (drugs, alcohol) Other potential triggers, according to the Journal of Psychiatric Research review, include: Supplements like St