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Selection was based on the following criteria: five significant-risk impurities, defined by a high EpiMatrix Score/low JanusMatrix Score (increased epitope content, reduced human homology, considered likely to be immunogenic), and two low-risk impurities defined by a reduced EpiMatrix Score/higher JanusMatrix Score (low immunogenicity was expected)

doi: 10.1016/j.survophthal.2019.07.001

Dondero, Andrology: Placebo-controlled, double-blind, cross-over trial of glutathione (GSH) therapy in male infertility, Human Reproduction, Volume 8, Issue 10, October 1993, Pages 16571662 *Adeoye O, Olawumi J, Opeyemi A, Christiania O