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74 This kind of activation, normally via oxidation/reduction by mixed function oxidases cytochrome p450 enzyme systems (CYP p450), is prevalent in the liver, but metabolizing systems are active in other tissues

Culty M, et al

Research involving GLP-1R KO mouse models and in vitro bone cell studies indicated that GLP-1Ra could be advantageous for bone health, even when weight loss is pharmacologically induced